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Table 1 Diversity of the fungal product portfolio

From: Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories

Fungus

Exemplar industrially relevant product(s)

Exemplar companies

Aspergillus niger

Enzymes (glucoamylases, proteases, glucosidases, catalases, phytases, pectinases)

Organic acids (e.g. citric acid, succinate)

Secondary metabolites

DSM (The Netherlands), Zymergen (USA), Novozymes A/S (Denmark)

COFCO, Ensign, RZBC Group, (People’s Republic of China)

Aspergillus oryzae

Enzymes (amylases)

Novozymes A/S (Denmark), Amano Enzyme Inc. (Japan), Gekkeikan Sake Company Ltd. (Japan)

Aspergillus terreus

Enzymes (xylanases)

Organic acids (itaconic acid)

Secondary metabolites (lovastatin)

Merck (USA), Pfizer (USA)

Acremonium chrysogenum

β-lactam antibiotics (cephalosporins)

DSM (The Netherlands), Sandoz (Austria), Astellas Pharma (Japan)

Blakeslea trispora

Vitamins (β-carotene)

Universal Foods Corporation (Japan), DSM (The Netherlands), Pharmacia & Upjohn (USA)

Fusarium venenatum

Mycoprotein

Quorn Foods (United Kingdom)

Ganoderma lucidum

Composite materials (construction material)

Imitation leather

Mycoworks (USA)

Thermotelomyces thermophila

Enzymes (cellulases, phytases, laccases)

Novozymes A/S (Denmark), BASF SE (Germany)

Penicillium chrysogenum

β-lactam antibiotics (penicillins)

Enzymes (glucose oxidase)

DSM (The Netherlands), Pharmacia & Upjohn (USA), Merck (USA)

Pleurotus ostreatus

Composite materials (packaging material, construction material)

Ecovative (USA)

Schizophyllum commune

Textiles

MycoTEX (The Netherlands)

Trichoderma reesei

Enzymes (cellulases and hemi-cellulases)

DuPont (USA), Iogen Energy Corporation (Canada)

AB Enzymes (Germany)

Roal Oy (Finland)

Ustilago maydis

Itaconic acid

Toray Industries (USA), BASF SE (Germany)

  1. Listed are fungal cell factories, key product(s), and companies that use each organism. Exemplar companies are meant only as a guide and were identified from published literature or patent databases. Note that this list is not exhaustive—for more examples, see [2]